Pemphigis Vulgaris
	Flaccid blisters that rupture easily, leaving a crusted lesion Blisters dissect laterally when pressed (Nickolsky sign) Common sites of involvement include the scalp, intertriginous areas and mouth Disease occurs in middle and old age An autoimmune disease characterized by circulating antibodies directed against the intercellular cement substance in the epidermis
	Histology: Acantholysis (dyshesion of individual keratinocytes), results in an intraepidermal blister; variable dermal infiltrate often with eosinophils

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