| Herpes Zoster Infection |
 | - Groups of vesicles arranged along the distribution of a cranial or spinal nerve
- Cutaneous and visceral dissemination from the original dermatome develops in some individuals, particularly immunocompromised patients
- Associated with localized or referred pain
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 | - Examination of material from the base of the vesicle (Tzanck preparation) will show characteristic multinucleate giant cells
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 | - Histology: Intraepidermal vesicles with diagnostic multinucleate giant cells in adjacent epidermis or adnexal structures
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