Erythema Multiforme
	Erythematous papules and plaques; target (bulls eye) lesion is diagnostic Lesions are typically on extremities and are symmetrical Mucous membranes (eyes and mouth) may be involved (erythema Multiforme major)
	Immunologic reaction triggered by circulating immune complexes Drugs (penicillin, barbiturates, phenytoin, sulfonamides) and infection (herpes simplex, Mycoplasma pneumoniae) most common etiologic agents implicated
	Histology: Dyskeratotic keratinocytes in the epidermis, vacuolization along the basement membrane, and a mild superficial perivascular infiltrate of mononuclear cells

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