Craniopharyngioma

Classic adamantinoma-like appearance of a craniopharyngioma. The pink region corresponds to brain tissue (BT) at the interface with the tumor and is mainly composed of reactive astrocytes. The tumor itself is composed of epithelial cells arranged around cystic spaces. The cells proximal ot the spaces are cuboidal in shape and arranged in palisades, above this cell layer the epithelium became squamous. Some cysts are empty but others contain keratin debris (K).